Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p009 | (1) | SRF2015

A model of tissue-engineered (3d) decidua to study the effects of environmental pollutants on endometrial physiology

Mannelli Chiara , Szostek Anna , Letta Francesca , Łukasik Karolina , Jankowska Katarzyna , Piotrowska-Tomala Katarzyna , Paulesu Luana Ricci , Skarzynski Dariusz Jan

The increasing exposure to environmental chemicals is a burden for human reproduction, and can alter endometrial functions and maternal–embryo interactions. The available in vitro endometrial models often fail to represent the complexity of cellular environment, cells shape and organization, and could give misleading results on the effects of environmental chemicals. Here, a tissue-engineered (3D) decidua was used as a toxicological model. Human stromal cells wer...